中醫藥瀏覽 TCM Profile
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藥材 | Compound | |
(+)-epicatechin 3-caffeoylquinic,acid 3-o-caffeoylquinic,acid baicalein baicalin chlorogenetic,acid Chlorogenic acid chlorogenic,acid chrysin combretastain,a4 coptisine coptision epiberberine epicatechin hormothamnione jatrorrhizine neo-chlorogenic,acid scutellarin wogonin wogonoside |
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參考文獻 [1] Burnett, B. P., Jia, Q., Zhao, Y., Levy, R. M., A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. JOURNAL OF MEDICINAL FOOD 2007, 10, 442-451 [2] Wang, C. Z., Li, X. L., Wang, Q. F., Mehendale, S. R., Su, Y. C., Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells Phytomedicine 2010, 17, 63-68 [3] Gao, J., Sanchez-Medina, A., Pendry, B. A., Hughes, M. J., et al., Validation of a HPLC method for flavonoid biomarkers in skullcap (Scutellaria) and its use to illustrate wide variability in the quality of commercial tinctures. J Pharm Pharm Sci 2008, 11, 77-87 [4] Hao, H., Aixia, Y., Dan, L., Lei, F., et al., Baicalin suppresses expression of Chlamydia protease-like activity factor in Hep-2 cells infected by Chlamydia trachomatis. Fitoterapia 2009, 80, 448-452 [5] Huen, M. S. Y., Leung, J. W. C., Ng, W., Lui, W. S., et al., 5,7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties. Biochemical Pharmacology 2003, 66, 125-132 [6] Kim, E. H., Shim, B., Kang, S., Jeong, G., et al., Anti-inflammatory effects of Scutellaria baicalensis extract via suppression of immune modulators and MAP kinase signaling molecules. J Ethnopharmacol 2009, 126, 320-331 [7] Liao, H. L., Hu, M. K., Synthesis and anticancer activities of 5,6,7-trimethylbaicalein derivatives. Chem Pharm Bull (Tokyo) 2004, 52, 1162-1165 [8] Shih, H. C., Hsu, C. S., Yang, L. L., In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root. Journal of Biomedical Science 2009 [9] Sonoda, M., Nishiyama, T., Matsukawa, Y., Moriyasu, M., Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. Journal of Ethnopharmacology 2004, 91, 65-68 [10] Nagai, T., Suzuki, Y., Tomimori, T., Yamada, H., Antiviral activity of plant flavonoid, 5,7,4'-trihydroxy-8-methoxyflavone, from the roots of Scutellaria baicalensis against influenza A (H3N2) and B viruses. Biol Pharm Bull. 1995, 18, 295-299 [11] Tarrago��, T., Kichik, N., Claasen, B., Prades, R., et al., Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Bioorganic & Medicinal Chemistry 2008, 16, 7516-7524 [12] Yin, L., Lu, B., Qi, Y., Xu, L., et al., Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. J Pharm Biomed Anal 2009, 49, 1101-1108 [13] Zhao, Y., Li, H., Gao, Z., Gong, Y., Xu, H., Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. European Journal of Pharmacology 2006, 536, 192-199 [14] Zhou, X. Q., Liang, H., Lu, X. H., Cai, S. Q., et al., [Flavonoids from Scutellaria baicalensis and their bioactivities]. Beijing Da Xue Xue Bao 2009, 41, 578-584. |