簡介中醫藥瀏覽 TCM Profile
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| 藥材 | Compound | |
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5alpha-Lanosta-7,9(11),24-triene-15alpha,26-dihydroxy-3-one beta-D-Glucan butyl ganoderate A butyl lucidenate N ergosta-7,22-diene-3beta-yl linoleate ergosta-7,22-diene-3beta-yl palmitate ergosta-7,22-diene-3beta-yl pentadecanoate ergosterol Ganoderenic acid A ganoderic acid A ganoderic acid B Ganoderic acid C1 Ganoderic acid C2 Ganoderic acid C6 ganoderic acid D Ganoderic acid delta Ganoderic acid DM ganoderic acid E Ganoderic acid epsilon ganoderic acid F Ganoderic acid G Ganoderic acid gamma ganoderic acid H Ganoderic acid I ganoderic acid T-Q Ganoderic acid theta Ganoderic acid TR Ganoderic acid zeta Ganoderic acid zta Ganoderiol A Ganoderiol F Ganodermadiol Ganodermanodiol Ganodermanontriol Ganodermatriol Ganodermnonol ganolucidic acid A Ganolucidic acid D Lucialdehyde A Lucialdehyde B Lucialdehyde C lucideic acid P lucidenic acid A lucidenic acid C lucidenic acid D2 lucidenic acid F lucidenic acid N lucidenolactone Lucidumol A Lucidumol B ludicenic acid E2 methly lucidenate L Methyl 8beta,9alpha-dihydroganoderate J methyl ganoderate A methyl ganoderate B methyl ganoderate D methyl ganoderate F methyl ganoderate H methyl Ganoderic acid DM methyl Ganoderic acid TR methyl lucidenate A methyl lucidenate D2 methyl lucidenate E2 methyl lucidenate F methyl lucidenate P methyl lucidenate Q Polysaccharide |
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| 參考文獻 [1] Yuan, J. P., Wang, J. H., Liu, X., Distribution of free and esterified ergosterols in the medicinal fungus Ganoderma lucidum. Appl Microbiol Biotechnol 2007, 77, 159-165 [2] Liu, J., Kurashiki, K., Shimizu, K., Kondo, R., 5alpha-reductase inhibitory effect of triterpenoids isolated from Ganoderma lucidum. Biol Pharm Bull 2006, 29, 392-395 [3] Liu, J., Kurashiki, K., Shimizu, K., Kondo, R., Structure-activity relationship for inhibition of 5alpha-reductase by triterpenoids isolated from Ganoderma lucidum. Bioorganic & Medicinal Chemistry 2006, 14, 8654-8660 [4] Liu, J., Shimizu, K., Konishi, F., Kumamotob, S., Kondoa, R., The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum. Bioorganic & Medicinal Chemistry 2007, 15, 4966-4972 [5] Yang, H. L., Chen, G. H., Li, Y. Q., A quantum chemical and statistical study of ganoderic acids with cytotoxicity against tumor cell. Eur J Med Chem 2005, 40, 972-976 [6] Jiang, J., Grieb, B., Thyagarajan, A., Sliva, D., Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med 2008, 21, 577-584 [7] Zhang, Q., Zuo, F., Nakamura, N., Ma, C. M., Hattori, M., Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum. J Nat Med 2009, 63, 304-310 [8] Wu, T. S., Shi, L. S., Kuo, S. C., Cytotoxicity of Ganoderma lucidum triterpenes. J Nat Prod 2001, 64, 1121-1122 [9] Ma, J., Ye, Q., Hua, Y., Zhang, D., et al., New lanostanoids from the mushroom Ganoderma lucidum. J Nat Prod 2002, 65, 72-75 [10] Iwatsuki, K., Akihisa, T., Tokuda, H., Ukiya, M., et al., Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation. J Nat Prod 2003, 66, 1582-1585 [11] Lee, I., Seo, J., Kim, J., Kim, H., et al., Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells. J Nat Prod 2010, 73, 172-176 [12] Ziegenbein, F. C., Hanssen, H. P., Konig, W. A., Secondary metabolites from Ganoderma lucidum and Spongiporus leucomallellus. Phytochemistry 2006, 67, 202-211 [13] Wang, J., Zhang, L., Structure and chain conformation of five water-soluble derivatives of a beta-D-glucan isolated from Ganoderma lucidum. Carbohydr Res 2009, 344, 105-112 [14] Wang, F. S., Cai, H., Yang, J. S., Zhang, Y. M., et al., STUDIES ON THE GANODERIC ACID,A NEW C0NSTITUENTS FR0M THE FRUITING B0DY 0F GANODERMA LUCIDUM (FR.)KARST. Acta Pharmaceutica Sinice 1997, 32, 447-450 [15] Liu, J., Shiono, J., Shimizu, K., Kukita, A., et al., Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitor. Bioorganic & Medicinal Chemistry Letters 2009, 19, 2154-2157 [16] Akihisa, T., Nakamuraa, Y., Tagataa, M., Tokudab, H., et al., Anti-Inflammatory and Anti-Tumor-Promoting Effects of Triterpene Acids and Sterols from the Fungus Ganoderma lucidum. CHEMISTRY & BIODIVERSITY 2007, 4, 224-231 [17] Miyamoto, I., Liu, J., Shimizu, K., Sato, M., et al., Regulation of osteoclastogenesis by ganoderic acid DM isolated from Ganoderma lucidum. Eur J Pharmacol 2009, 602, 1-7 [18] Adams, M., Christen, M., Plitzko, I., Zimmermann, S., et al., Antiplasmodial lanostanes from the Ganoderma lucidum mushroom. J Nat Prod 2010, 73, 897-900 [19] Wu, T. S., Shi, L. S., Kuo, S. C., Cherng, C. Y., et al., Platelet Aggregation Inhibitor from Ganoderma lucidum. Journal of the Chinese Chemical Society 1997, 44, 157-161. |
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